Dimer and Superstructure of the Active Form of a Vitamin D3. 1.ALPHA.,24(R)Dihydroxy-vitamin D3 Monohydrate, C27O3H44 H2O.
نویسندگان
چکیده
منابع مشابه
Identification of 1,25-dihydroxycholecalciferol, a form of vitamin D3 metabolically active in the intestine.
A biologically active vitamin D(3) metabolite ("peak V metabolite") more polar than 25-hydroxycholecalciferol has been isolated from chicken intestines in pure form as a mono(trimethylsilyl)ether derivative. The molecule has been identified as 1,25-dihydroxycholecalciferol by means of mass spectrometry, ultraviolet absorption spectrophotometry, and specific chemical reactions.
متن کاملThe role of vitamin D3 and vitamin B9 (Folic acid) in immune system
Background and aims: Vitamins are essential constituents of our diet that Longley have been known to influence the immune system. Vitamin D3 and B9 have received particular attention in recent years as these vitamins have been shown to have an unexpected and crucial effect on the immune response. 1, 25(OH)2D3 metabolizing enzymes and vitamin D r...
متن کاملVitamin D3 and brain development.
Evidence for the presence of the vitamin D receptor in brain implies this vitamin may have some function in this organ. This study investigates whether vitamin D(3) acts during brain development. We demonstrate that rats born to vitamin D(3)-deficient mothers had profound alterations in the brain at birth. The cortex was longer but not wider, the lateral ventricles were enlarged, the cortex was...
متن کاملA rapidly acting metabolite of vitamin D3.
A vitamin D(3) metabolite in intestine more polar than 25-hydroxy-vitamin D(3)(25-OH D(3)) has been detected by countercurrent distribution. The intestinal metabolite is found also after administration of labeled hydroxy D(3), indicating that it arises from vitamin D(3) via the intermediate 25-hydroxy derivative. The more polar metabolite is localized in the nuclear-chromatin fraction and appea...
متن کاملSpecific binding protein for active metabolites of vitamin D3.
FIG. 1 Separation of the specific protein binding with vitamin D3 and its metabolites in rat intes tinal cytoplasm by gel filtration on Sephadex G 200 after the administration of vitamin D3-3H in vivo. 1,000I.U. (3•~105cpm) of randomly labeled vitamin D3 (sp. act. 1.2•~104cpm/ug) was injected intracar dially to vitamin D deficient rat 16 hours before decapitation. 2.0 ml of rat intestinal cytop...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2001
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.49.305